Case study

King’s College Hospital

Design & build brand new Cell Therapy Unit at King’s College Hospital

3D model of cell therapy unit
Grade B islets process room with 3 no. MSC’s and continuous particle
Grade D cell therapy preparation area. Fixed furniture, GRP doors and pass through to virus suites
Viral gene therapy change room with step over bench and inflatable seal door
Grade D material staging corridor

The details

Our role:

GMP Design and Build Specialist

Scope:

M&E + Construction

Facility type:

Cell Therapy Unit

Floor area:

345 m²

Contract value:

£1.6m

Programme:

10 months

Enbloc were chosen to design and build a new Cell Therapy Unit on the second floor of King’s College Hospital, London due to our past experience in large scale cleanroom projects. The Cell Therapy Unit which is a ground breaking facility which is understood to be the first of its kind in the UK. The facility pioneers new Cell Therapies for people living with Diabetes, Leukaemia and Liver Failure.

The suite consists of 26 rooms including Grade B, C & D cleanrooms, support , packing and waste treatment areas. The suite has been designed to maintain effective biological and operational segregation by using fully welded vinyl gas tight construction, time delayed access control and dedicated change areas.

A complex HVAC control system involving multiple dedicated extract fans, multiple independent gas tight HVAC zones, dynamic air volume control and an integrated HPV gassing systems has been installed to allow room sterilization to be carried out whilst adjacent rooms continue to operate. There are 6 no. Microbiological Safety Cabinets and 6 no. Isolators. The Isolators and Grade B rooms have continuous particle monitoring and all rooms have temperature and pressure monitoring.

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